If Rey fills in for Undertaker who might go down with injury, expect Punk and Rey to go at it most of that match which would leave Big Show and Swagger to go at it. I cannot see Swagger beating Big Show clean, as much as I hate Big Show I just can't see it. Fatal 4 Ways are no DQ though, so that could play to his advantage. This is a must win for Swagger, much like every title defense he has had thus far. Though he has been champ for quite sometime, it is not long enough to cement him as a legit main eventer. Most times I still don't see Punk in the WWE MAIN EVENT league based off his previous two title reigns.
I don't see Cena losing though. If anything he will lose to Sheamus at Fatal Four Way or even the next PPV. I don't see Edge or Orton getting it. Edge just flat out doesn't deserve it and I don't think putting the belt on Orton yet is a good idea. Sheamus could get it since I would say he needs another reign to build up his rep on Raw plus it would be a huge opening for HHH to come back in the summer and challenge Sheamus for the belt. I know it isn't that cool, but atleast people won't bitch about having Cena still in the main event.