Naughty Dog did Uncharted one of my favorite new gen series so I'm hopefully for this. With that, I'm sure the presentation and story should be great, but there going to have to do something different in terms of gameplay to make it stand out.
If it's a survival/end of world type of game would love to see it focus not so much on gun play, but instead have there be a limited amount of ammo, less gun play and more stealth and strategy.