Part of me wants to say "Definitely if you have the WR depth. You're trading an RB1 and a starting-caliber WR for a slightly better WR1."
But then again, in this league if I was still having issues at RB2 and you offered me Forsett and Benjamin for AJ Green, I'd almost certainly say no, and you know how highly I value Forsett.
Now that PC is working I'm tempted to do a "wrestler to fantasy team" comparison. For now, lets see if you can inspire me to set up a deal of my own. Come on baby, buy high on Ryan Mathews