I say first off, TAKE THE DAMN TITLE FROM SANTINO, second I think they should just replace the US title for something else. Maybe the Light Heavyweight or TV titles since they have rules and are just more interesting then the US title. With the Light Heavyweight you can give light heavyweights a chance at the belt and make them actually look like something. The TV title you defend every week, give it in the hands of new talent that hasn't caught everyone's interest yet(example: Damien Sandow, Justin Gabriel, etc.) and they get more TV time. That way the lower midcards get a title that'll help them out instead of being a waste. And then the who titles setup could be like this: You become TV Champion to show off your skills. After a good month or few, lose the title. You're still to new to go after the World title(which I think there should only be one) but you still want to prove you're great, so you go after the IC champion. The IC champion will always get recognized because he has a belt. Anybody with a title always gets recognized by fans because they have one of the championships, plain and simple.
After a feud with a couple of people and back and forth winning and losing the IC title a couple of times, stop going after that title and go after a world title. Kinda like Cody Rhodes, feud with Christian and try to get the IC title back, but you don't, and now you're getting a chance to win a match and go after the World title. Pretty much you're goal from now is to get the World title, unless you form a team with someone, but that's a different story. After I say about 6 or 7 years of winning and losing the world title, go after the IC title once more, just to put over new talent and to being prestige to the IC title, since having a former World Champion would make the title seem much more interesting. As for winning the IC title and getting a future World title shot like the X Division title in Impact Wrestling, no that shouldn't happen.