Personally I think running an e-fed is easy. I've been running one for about a month now on a different forum that plenty of CWF guys also participate in and I've loved the extra responsibility. I organised the fuck out of the place and I think it's running pretty damn well, but the only issue is people posting frequently.
An RP e-fed would probably be the better way to go, rather than another TT (trash talk) one. I've participated in an RP fed before and tend to give it a bit of a go, but a lot of the time it really isn't my thing.