Due to my personal preferences I'm much more familiar with voice actors but for the sake of this thread I'll ignore those. When I do watch live action shows (I know this doesn't just pertain to shows but I don't really watch enough movies to judge solely on that), it's generally sitcom/comedies so pretty much everyone here will be in that domain so keep that in mind. Anyway off the top of my head, Michael J. Fox is probably my favorite. Loved him in the Back To The Future franchise (easily my favorite movie franchise which isn't that impressive since it's only real competition is The Dark Knight Trilogy) and in Spin City (which is probably my favorite role from him). Pretty excited for his new sitcom coming out. I can throw out plenty of other actors/actresses but honestly, I'm only familiar with most of them through one role and it feels kind of stupid to me to label someone as one of my favorites if I've only witnessed one role by them, regardless of how well they performed.