Depends on what plans they have for Cena heading into Wrestlemania, really. If he really is facing off with Wyatt or teaming with Hogan to face off against the entire family (the second one being my own prediction), then they could come in and cost him the match at the Rumble as a way of getting that feud off and going. The logic could be that while Cena feuds with Orton leading up to the PPV, maybe he has this side thing happening as well where he tries to snap Bryan back to his senses and get him to leave the Wyatt Family and thus ruffles their feathers in the process (especially if Cena actually IS the reason Bryan turns on them before the PPV.) This leads to their interference in the title match at the Rumble.
If Cena fights Triple H at Mania, then he will personally cost him the match somehow. Either way, look forward to Orton walking out as champion unless they do decide to go with Cena/Lesnar for Mania, in which case Cena will win the title (kind of stupid after taking a clean loss in the unification match at TLC but whatever.)