I wanna say yes, but it would really depend on the opponent.
Austin's first real feud as Stone Cold was calling out Bret Hart until Bret returned and accepted a match with Austin at the '96 Survivor Series, and their feud was off and running after that. This is the kind of angle that should lead to Austin returning for one more match - someone having the balls to call Austin out and him eventually returning for a confrontation of some kind. Considering Austin was a non-main event talent when he called out Bret Hart and it was the Bret Hart feud that first put over Austin hugely, it would make sense to do the same for a younger superstar this time around. Of course Austin would win the match but then so did Bret Hart against Austin - defeated him at both Survivor Series and Wrestlemania 13. It didn't matter, Austin still got the rub and so would the younger superstar with Austin this time around.
Unfortunately, I can't think of a newer talent that would work in this role (Daniel Bryan, Dolph Ziggler, even CM Punk... I don't see it.) Brock Lesnar is the only person I can see it working with. Who else projects the image of a tough guy and bad ass you really wouldn't want to mess with than Lesnar? Even if Lesnar loses a ton of matches during his time here (including to Punk, even), there is still no one more convincing to call Austin out than Lesnar and Heyman. There is even a set up for Lesnar challenging Austin here:
If this is the match that goes down, I think it would make the most sense to have the match occur at Wrestlemania 31 considering that's when Brock's contract runs up. Brock and Heyman's logic could be that Brock has run through everyone and Heyman says that the WWE Universe doesn't deserve to see someone like Lesnar perform and so he wants to destroy one last hero of the WWE universe before he leaves for good, and his choice of opponent is the opponent of all opponents - Steve Austin.
I'd love for it to be someone else, someone who could use a rub from working with Austin. But if there is no one else, then Lesnar is the best choice, if WWE simply wants a big time match up that will draw huge.